Alternative splicing caused by RNA secondary structure
نویسندگان
چکیده
منابع مشابه
Conserved RNA secondary structures promote alternative splicing.
Pre-mRNA splicing is carried out by the spliceosome, which identifies exons and removes intervening introns. Alternative splicing in higher eukaryotes results in the generation of multiple protein isoforms from gene transcripts. The extensive alternative splicing observed implies a flexibility of the spliceosome to identify exons within a given pre-mRNA. To reach this flexibility, splice-site s...
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ژورنال
عنوان ژورنال: Cell
سال: 1985
ISSN: 0092-8674
DOI: 10.1016/0092-8674(85)90239-9